Regulatory Genes and Drug Sensitivity
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چکیده
منابع مشابه
Regulatory genes and drug sensitivity.
Many of the genes commonly associated with cancer participate in the regulation of cell proliferation and apoptosis. Alteration of these genes leads to molecular regulatory defects that are thought to drive the neoplastic process. But could the alterations also affect the response to chemotherapy? Hochhauser et al. (7) in this issue of the Journal address this question for the case of cyclin Dl...
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The role of regulatory drug submission evaluators in Canada is to critically assess both the data submitted and the sponsor's interpretation of the data in order to reach an evidence-, and context-based recommendation as to the potential benefits and potential harms (i.e., risks) associated with taking the drug under the proposed conditions of use. The purpose of this document is to outline the...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 1996
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/88.18.1255